Tg(Hand2-cre)7-1Clou
Transgene Detail

Summary

• Symbol: Tg(Hand2-cre)7-1Clou
• Name: transgene insertion 7-1, David E Clouthier
• MGI ID: MGI:3056567
• Synonyms: dHAND-Cre, Hand2-Cre, Tg(Hand2-cre)#Clou
• Transgene: Tg(Hand2-cre)7-1Clou Location: unknown
• Alliance: Tg(Hand2-cre)7-1Clou page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hand2-cre)7-1Clou expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Hand2

• Mutation details: A 7.4 kb of the Hand2 upstream region, containing the pharyngeal arch and cardiac enhancer elements, was fused to Cre cDNA containing a nuclear localization signal (NLS) and SV40-pA. Two lines were created (7-1 and 7-2), with expression of line 7-2 being less intense than that of line 7-1. (J:83364)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hand2 (species not specified) Summary of all recombinase alleles driven by Hand2. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

9 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:83364 Ruest LB, et al., Dhand-cre transgenic mice reveal specific potential functions of dHAND during craniofacial development. Dev Biol. 2003 May 15;257(2):263-77
• All: 9 reference(s)