Tg(H2KePCC)2403Stoe
Transgene Detail

Summary

• Symbol: Tg(H2KePCC)2403Stoe
• Name: transgene insertion 2403, Stephan Oehen
• MGI ID: MGI:3056679
• Synonyms: ePCC
• Transgene: Tg(H2KePCC)2403Stoe Location: unknown
• Alliance: Tg(H2KePCC)2403Stoe page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2KePCC)2403Stoe expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  pigeon	PCC

• Mutation details: Pigeon cytochrome c was engineered for expression in lymphoid tissues of transgenic mice in two forms. The cytochrome C in this construct is targeted to the mitochondria after cytoplasmic synthesis (ePCC). mRNA expression levels are lower in mice carrying this transgene than in mice carrying Tg(H2KmPCC)2939. PCC was expressed in thymus, spleen and LPS stimulated B cells as determined by Northern blot. (J:92997)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92997 Oehen S, et al., Antigen compartmentation and T helper cell tolerance induction. J Exp Med. 1996 Jun 1;183(6):2617-26
• All: 2 reference(s)