Tg(LckNotch1)9Erob
Transgene Detail

Summary

• Symbol: Tg(LckNotch1)9Erob
• Name: transgene insertion 9, Ellen Robey
• MGI ID: MGI:3056811
• Synonyms: lck-N^ic
• Transgene: Tg(LckNotch1)9Erob Location: unknown
• Alliance: Tg(LckNotch1)9Erob page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(LckNotch1)9Erob expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Notch1 (MGI:97363)

• Mutation details: The transgene expresses an activated form of Notch fused to a FLAG epitope under the control of the thymocyte specific Lck proximal promoter. (J:93005)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:93005 Robey E, et al., An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell. 1996 Nov 1;87(3):483-92
• All: 11 reference(s)