Tg(Th-TAg)17Dmc
Transgene Detail

Summary

• Symbol: Tg(Th-TAg)17Dmc
• Name: transgene insertion 17, Dona M Chikaraishi
• MGI ID: MGI:3057175
• Transgene: Tg(Th-TAg)17Dmc Location: unknown
• Alliance: Tg(Th-TAg)17Dmc page

Transgene origin

• Strain of Origin: (C57BL/6NTac x DBA/2NTac)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the rat tyrosine hydroxylase promoter and the wild-type allele of the SV40 large T antigen (TAg) gene. The construct also includes the rat tyrosine hydroxylase enhancer. (J:90323)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Th-TAg)17Dmc

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

This founder female died of a massive adrenal tumor at 10 weeks of age during pregnancy. This line was not further propagated.

References

• Original: J:90323 Suri C, et al., Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. J Neurosci. 1993 Mar;13(3):1280-91
• All: 1 reference(s)