Grm1^rcw-2J
Spontaneous Allele Detail

Summary

• Symbol: Grm1^rcw-2J
• Name: glutamate receptor, metabotropic 1; recoil wobbler 2 Jackson
• MGI ID: MGI:3057287
• Gene: Grm1 Location: Chr10:10561803-10958100 bp, - strand Genetic Position: Chr10, 3.44 cM, cytoband A2
• Alliance: Grm1^rcw-2J page

Mutation origin

• Strain of Origin: B6.129X1-Bax^tm1Sjk/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: This spontaneous mutation was found to be allelic with rcw by complementation testing versus the original mutation. Exon 4 has been duplicated. This results in a frame shift causing 23 missense amino acids beginning at position 396 and a stop codon at position 419. (J:127311)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grm1 Mutation: 81 strains or lines available

References

• Original: J:97119 Cook SA, et al., Recoil Wobbler 2 Jackson, rcw^2J, a new neurological mutation in the proximal region of mouse Chromosome 10. MGI Direct Data Submission. 2004
• All: 2 reference(s)