Fhit^tm1Tko
Targeted Allele Detail

Summary

• Symbol: Fhit^tm1Tko
• Name: fragile histidine triad gene; targeted mutation 1, MM Taketo
• MGI ID: MGI:3057316
• Synonyms: Fhit^-
• Gene: Fhit Location: Chr14:11307738-12919681 bp, + strand Genetic Position: Chr14, 5.61 cM, cytoband A2
• Alliance: Fhit^tm1Tko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93269
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-neo replaced exon 5. (J:93269)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Fhit^tm1Tko

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fhit Mutation: 22 strains or lines available

References

• Original: J:93269 Fujishita T, et al., Development of spontaneous tumours and intestinal lesions in Fhit gene knockout mice. Br J Cancer. 2004 Nov 18;91(8):1571-4
• All: 1 reference(s)