Tg(GFAP-cre)#Gtm
Transgene Detail

Summary

• Symbol: Tg(GFAP-cre)#Gtm
• Name: transgene insertion #, David H Gutmann
• MGI ID: MGI:3057344
• Synonyms: GFAP-cre, GFAPCreLacZ
• Transgene: Tg(GFAP-cre)#Gtm Location: unknown
• Alliance: Tg(GFAP-cre)#Gtm page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(GFAP-cre)#Gtm expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  GFAP (2670)

  Gfap	(MGI:95697)

• Mutation details: This transgene expresses Cre recombinase and beta-galactosidase under the control of the human glial fibrillary acidic (GFAP) promoter. This transgene is expressed in astrocytes by embryonic day 14.5. (J:77208)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	GFAP (human) Summary of all recombinase alleles driven by GFAP. Alliance human GFAP gene page

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(GFAP-cre)#Gtm

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:77208 Bajenaru ML, et al., Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Mol Cell Biol. 2002 Jul;22(14):5100-13
• All: 61 reference(s)