Pomt1^tm1Jec
Targeted Allele Detail

Summary

• Symbol: Pomt1^tm1Jec
• Name: protein-O-mannosyltransferase 1; targeted mutation 1, Jesus Cruces
• MGI ID: MGI:3497739
• Synonyms: Pomt1^-
• Gene: Pomt1 Location: Chr2:32126602-32145017 bp, + strand Genetic Position: Chr2, 22.09 cM
• Alliance: Pomt1^tm1Jec page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93435
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2, containing the start codon, was replaced by a neomycin resistance gene via homologous recombination. (J:93435)

Expression

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pomt1 Mutation: 48 strains or lines available

References

• Original: J:93435 Willer T, et al., Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality. (Correction: 2004;101(45):16081). Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14126-31
• All: 2 reference(s)