Neurog3^tm1.1Ggr
Targeted Allele Detail

Summary

• Symbol: Neurog3^tm1.1Ggr
• Name: neurogenin 3; targeted mutation 1.1, Gerard Gradwohl
• MGI ID: MGI:3505733
• Synonyms: Ngn3^EYFP
• Gene: Neurog3 Location: Chr10:61968869-61970542 bp, + strand Genetic Position: Chr10, 32.35 cM, cytoband B4
• Alliance: Neurog3^tm1.1Ggr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93570
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting construct was designed to insert an IRES-EYFP and a floxed puromycin resistance cassette downstream of the coding sequence. Crossing with mice expressing Cre in the germ line excised the puromycin resistance gene. (J:93570)

Expression

In Mice Carrying this Mutation:

2 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Neurog3 Mutation: 19 strains or lines available

References

• Original: J:93570 Mellitzer G, et al., Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice. Mol Endocrinol. 2004 Nov;18(11):2765-76
• All: 13 reference(s)