Tg(Myl2SLC2A1)2Mue
Transgene Detail

Summary

• Symbol: Tg(Myl2SLC2A1)2Mue
• Name: transgene insertion 2, Mike M Mueckler
• MGI ID: MGI:3505739
• Synonyms: MLC-Glut1b
• Transgene: Tg(Myl2SLC2A1)2Mue Location: unknown
• Alliance: Tg(Myl2SLC2A1)2Mue page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myl2SLC2A1)2Mue expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SLC2A1 (6513)

  Slc2a1

  (MGI:95755)

• Mutation details: The transgene contains the rat Myl2 (myosin light chain 2) promoter, a cDNA sequence encoding human SLC2A1, a segment of human albumin intron 1 and a human GAPD (glyceraldehyde-3-phosphate dehydrogenase) polyadenylation site. (J:93868)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:93868 Marshall BA, et al., Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle. J Biol Chem. 1993 Sep 5;268(25):18442-5
• All: 3 reference(s)