Summary |
|
|||||||||||||
Variant origin |
|
|||||||||||||
Variant description |
|
|||||||||||||
Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
|
|||||||||||||
Expression |
|
|||||||||||||
Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:93070Linkage analysis was performed on 275 animals from a (NMRI8/Fbn x DBA/2OlaHsd)F2 intercross to identify QTLs associated with post-weaning body weight and body composition. Parental strain NMRI8/Fbn is 2.5 times heavier than parental strain DBA/OlaHsd, and also exhibits increased muscle and organ weight at 6 weeks of age and 4.6 times the amount of reproductive fat of DBA/2OlaHsd. 92 microsatellite markers were used for the genome scan. An interval on mouse Chromosome 8 from 57 cM - 66 cM showed linkage to early body weight at 2, 3, and 4 weeks of age. These QTLs were designated Bwnd2wk5 (57 cM), Bwnd3wk1 (66 cM), and Bwnd4wk4 (66 cM). NMRI8/Fbn-derived alleles confer increased body weight with a dominant or additive mode of inheritance at these loci. |
|||||||||||||
References |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 10/29/2024 MGI 6.24 |
|
|