Tg(Alb1HBV)43Bri
Transgene Detail

Summary

• Symbol: Tg(Alb1HBV)43Bri
• Name: transgene insertion 43, Ralph L Brinster
• MGI ID: MGI:3510558
• Synonyms: 45-2, 45.2, Tg(Alb-1HBV)Bri43, Tg(Alb1-HBVL)43Bri
• Transgene: Tg(Alb1HBV)43Bri Location: unknown
• Alliance: Tg(Alb1HBV)43Bri page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The mouse albumin promoter was used to drive high levels of hepatitis B virus large envelope gene expression in hepatocytes. Approximately 40-50% of hepatocytes expressed the transgene in an area limited to the periphery of the hepatic lobule. (J:86165)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:86165 Chisari FV, et al., Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell. 1989 Dec 22;59(6):1145-56
• All: 3 reference(s)