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Tg(Alb1HBV)141Bri
Transgene Detail
Summary
Symbol: Tg(Alb1HBV)141Bri
Name: transgene insertion 141, Ralph L Brinster
MGI ID: MGI:3510593
Synonyms: 45-3, Tg(Alb-1HBV)Bri141, Tg(Alb1-HBVL)141Bri
Transgene: Tg(Alb1HBV)141Bri  Location: unknown  
Alliance: Tg(Alb1HBV)141Bri page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe mouse albumin promoter was used to drive high levels of hepatitis B virus large envelope gene expression in hepatocytes. Approximately 15-20% of hepatocytes expressed the transgene, with expression limited to a thin zone at the periphery of the hepatic lobule. (J:86165)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:86165 Chisari FV, et al., Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell. 1989 Dec 22;59(6):1145-56
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory