Traf3ip2^tm1Lix
Targeted Allele Detail

Summary

• Symbol: Traf3ip2^tm1Lix
• Name: TRAF3 interacting protein 2; targeted mutation 1, Xiaoxia Li
• MGI ID: MGI:3510783
• Synonyms: Act1^flox
• Gene: Traf3ip2 Location: Chr10:39488930-39531303 bp, + strand Genetic Position: Chr10, 20.86 cM
• Alliance: Traf3ip2^tm1Lix page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93923
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to flank exon 2 with loxP sites as well as insert a neomycin resistance gene and an additional 5' loxP site into intron 1. (J:93923)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Traf3ip2 Mutation: 41 strains or lines available

References

• Original: J:93923 Qian Y, et al., Act1, a negative regulator in CD40- and BAFF-mediated B cell survival. Immunity. 2004 Oct;21(4):575-87
• All: 9 reference(s)