Summary |
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Transgene origin |
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Transgene description |
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Find Mice (IMSR) |
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Notes |
Three transgenic founder lines were established. Transgenic line BK5.erbB2A displayed the highest level of transgene expression and was used for all experiments. By 6 months of age, 10% of hemizygous BK5.erbB2A animals and 90% of homozygous BK5.erbB2A animals developed spontaneous papillomas.
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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