Il6st^tm1Mam
Targeted Allele Detail

Summary

• Symbol: Il6st^tm1Mam
• Name: interleukin 6 signal transducer; targeted mutation 1, Lothar Hennighausen
• MGI ID: MGI:3511264
• Synonyms: gp130^fl, Il6st^tm1Lgp
• Gene: Il6st Location: Chr13:112600604-112643394 bp, + strand Genetic Position: Chr13, 63.73 cM
• Alliance: Il6st^tm1Mam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93986
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted into the promoter and intron 2. (J:93986)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il6st Mutation: 80 strains or lines available

References

• Original: J:93986 Zhao L, et al., Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK. J Biol Chem. 2004 Oct 15;279(42):44093-100
• All: 5 reference(s)