Chd7^Flo
Chemically induced Allele Detail

Summary

• Symbol: Chd7^Flo
• Name: chromodomain helicase DNA binding protein 7; flouncer
• MGI ID: MGI:3511552
• Synonyms: WBE2
• Gene: Chd7 Location: Chr4:8690406-8867659 bp, + strand Genetic Position: Chr4, 3.68 cM
• Alliance: Chd7^Flo page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: A mutation in the splice donor site resulted in the S1864X substitution. This mutation putatively results in a protein lacking only the most C-terminal NLS, SANT, and BRK domains. (J:104123)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Chd7 Mutation: 138 strains or lines available

References

• Original: J:93173 Pau H, et al., Characterization of a new mouse mutant, flouncer, with a balance defect and inner ear malformation. Otol Neurotol. 2004 Sep;25(5):707-13
• All: 2 reference(s)