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Aldh1a3tm1Gdu
Targeted Allele Detail
Summary
Symbol: Aldh1a3tm1Gdu
Name: aldehyde dehydrogenase family 1, subfamily A3; targeted mutation 1, Gregg Duester
MGI ID: MGI:3512079
Synonyms: Raldh3-
Gene: Aldh1a3  Location: Chr7:66040640-66077225 bp, - strand  Genetic Position: Chr7, 35.73 cM, cytoband C
Alliance: Aldh1a3tm1Gdu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108515
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 11 was removed via cre mediated recombination. Retinoic acid activity was absent from the ventral retina and olfactory pit at E10.5. (J:108515)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 29 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aldh1a3 Mutation:  26 strains or lines available
References
Original:  J:108515 Molotkov A, et al., Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. Development. 2006 May;133(10):1901-10
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory