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Slc39a3tm1Gka
Targeted Allele Detail
Summary
Symbol: Slc39a3tm1Gka
Name: solute carrier family 39 (zinc transporter), member 3; targeted mutation 1, Glen K Andrews
MGI ID: MGI:3512105
Synonyms: ZIP3-
Gene: Slc39a3  Location: Chr10:80864374-80873169 bp, - strand  Genetic Position: Chr10, 39.72 cM
Alliance: Slc39a3tm1Gka page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99161
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region of the gene following the translation initiating ATG has been deleted and replaced by an EGFP open reading frame followed by a loxP-flanked neomycin selection cassette. Expression of EGFP is driven by the endogenous promoter. (J:99161)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc39a3 Mutation:  12 strains or lines available
Notes
Double mutant subjects were day E14 embryos from matings of mice homozygous for both mutations whose dams were fed a zinc-deficient diet from day 8 of pregnancy.
References
Original:  J:99161 Dufner-Beattie J, et al., Generation and Characterization of Mice Lacking the Zinc Uptake Transporter ZIP3. Mol Cell Biol. 2005 Jul;25(13):5607-15
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory