Pla2g10^Gt712Lex
Gene trapped Allele Detail

Summary

• Symbol: Pla2g10^Gt712Lex
• Name: phospholipase A2, group X; gene trap 712, Lexicon Genetics
• MGI ID: MGI:3512106
• Synonyms: Pla2g10^Gt()Mhg, sPLA2-X^-
• Gene: Pla2g10 Location: Chr16:13532921-13548847 bp, - strand Genetic Position: Chr16, 9.5 cM
• Alliance: Pla2g10^Gt712Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125607
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector was inserted between exons 3 and 4. The absence of protein product was confirmed by western blot analysis on stomach lysates. This is a null allele. (J:125607)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pla2g10 Mutation: 31 strains or lines available

References

• Original: J:125607 Henderson WR Jr, et al., Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model. J Exp Med. 2007 Apr 16;204(4):865-77
• All: 3 reference(s)