Cdk2ap1^tm1Dtw
Targeted Allele Detail

Summary

• Symbol: Cdk2ap1^tm1Dtw
• Name: cyclin dependent kinase 2 associated protein 1; targeted mutation 1, David T Wong
• MGI ID: MGI:3512185
• Gene: Cdk2ap1 Location: Chr5:124483502-124492691 bp, - strand Genetic Position: Chr5, 63.53 cM
• Alliance: Cdk2ap1^tm1Dtw page

Craniofacial abnormality of surviving Cdk2ap1^tm1Dtw/Cdk2ap1^tm1Dtw and Cdk2ap1^tm1Dtw/Cdk2ap1⁺ mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146277
• Parent Cell Line: LW1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exons 2 and 3 were replaced with a cystosine deaminase and neo cassette. (J:146277)

Generation of the Cdk2ap1^tm1Dtw allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdk2ap1 Mutation: 62 strains or lines available

References

• Original: J:146277 Kim Y, et al., Targeted inactivation of p12, CDK2 associating protein 1, leads to early embryonic lethality. PLoS One. 2009;4(2):e4518
• All: 3 reference(s)