Nqo2^tm1Bout
Targeted Allele Detail

Summary

• Symbol: Nqo2^tm1Bout
• Name: N-ribosyldihydronicotinamide quinone reductase 2; targeted mutation 1, Jean A Boutin
• MGI ID: MGI:3512531
• Synonyms: Nqo^-
• Gene: Nqo2 Location: Chr13:34148670-34172426 bp, + strand Genetic Position: Chr13, 14.01 cM, cytoband A4
• Alliance: Nqo2^tm1Bout page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94264
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 2 and 3 were deleted after homologous recombination and Cre-mediated recombination. (J:94264)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nqo2 Mutation: 21 strains or lines available

References

• Original: J:94264 Mailliet F, et al., Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT3. FEBS Lett. 2004 Dec 3;578(1-2):116-20
• All: 3 reference(s)