Disp1^tm2Amc
Targeted Allele Detail

Summary

• Symbol: Disp1^tm2Amc
• Name: dispatched RND transporter family member 1; targeted mutation 2, Andrew P McMahon
• MGI ID: MGI:3512541
• Synonyms: Disp1^delta2C
• Gene: Disp1 Location: Chr1:182867830-183003086 bp, - strand Genetic Position: Chr1, Syntenic
• Alliance: Disp1^tm2Amc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94270
• Parent Cell Line: AV3 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to flank exon 2, which encodes the amino terminal cytoplasmic domain and the first transmembrane domain, with loxP sites. (J:94270)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Disp1 Mutation: 61 strains or lines available

References

• Original: J:94270 Tian H, et al., Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development. 2005 Jan;132(1):133-42
• All: 2 reference(s)