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Disp1tm2Amc
Targeted Allele Detail
Summary
Symbol: Disp1tm2Amc
Name: dispatched RND transporter family member 1; targeted mutation 2, Andrew P McMahon
MGI ID: MGI:3512541
Synonyms: Disp1delta2C
Gene: Disp1  Location: Chr1:182867830-183003086 bp, - strand  Genetic Position: Chr1, Syntenic
Alliance: Disp1tm2Amc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94270
Parent Cell Line:  AV3 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to flank exon 2, which encodes the amino terminal cytoplasmic domain and the first transmembrane domain, with loxP sites. (J:94270)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Disp1 Mutation:  61 strains or lines available
References
Original:  J:94270 Tian H, et al., Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development. 2005 Jan;132(1):133-42
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory