Enam^abte
Chemically induced Allele Detail

Summary

• Symbol: Enam^abte
• Name: enamelin; abnormal tooth enamel
• MGI ID: MGI:3512772
• Synonyms: ate, ATE1, Enam^ATE1
• Gene: Enam Location: Chr5:88635834-88653908 bp, + strand Genetic Position: Chr5, 43.66 cM, cytoband E2
• Alliance: Enam^abte page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The molecular lesion is a C-to-T substitution at position 826 of the cDNA, resulting in the introduction of a stop codon at amino acid 176 of the encoded protein. (J:82809)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enam Mutation: 71 strains or lines available

References

• Original: J:92107 Seedorf H, et al., Amelogenesis imperfecta in a new animal model--a mutation in chromosome 5 (human 4q21). J Dent Res. 2004 Aug;83(8):608-12
• All: 4 reference(s)