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Eif4g3repro8
Chemically induced Allele Detail
Summary
Symbol: Eif4g3repro8
Name: eukaryotic translation initiation factor 4 gamma, 3; reproductive mutant 8, JAX Reproductive Mutagenesis Program
MGI ID: MGI:3512906
Synonyms: G1-419-52
Gene: Eif4g3  Location: Chr4:137719090-137934397 bp, + strand  Genetic Position: Chr4, 70.02 cM
Alliance: Eif4g3repro8 page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis phenotypic mutant was identified in an ENU mutagenesis screen at the Jackson Laboratory. The mutation was identified as a G-to-C transversion. This causes a mis-sense mutation in the W2 domain of the encoded protein, producing an amino acid change from alanine to proline. (J:159444)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eif4g3 Mutation:  107 strains or lines available
References
Original:  J:92463 JAX Reproductive Mutagenesis Program, Heritable mouse mutants from The Jackson Laboratory Reproductive Genomics Mutagenesis Program. MGI Direct Data Submission. 2004-7;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory