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Marf1m1Rpg
Chemically induced Allele Detail
Summary
Symbol: Marf1m1Rpg
Name: meiosis regulator and mRNA stability 1; mutation 1, The Jackson Laboratory Reproductive Genomics Program
MGI ID: MGI:3512917
Synonyms: G1-375-18, marf1, Marf1ENU, Marf1ENU375-18
Gene: Marf1  Location: Chr16:13927030-13977157 bp, - strand  Genetic Position: Chr16, 9.69 cM
Alliance: Marf1m1Rpg page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis phenotypic mutant was identified in an ENU mutagenesis screen. The molecular lesion is a G-to-T transversion mutation at the 5' splice donor site of the 16th intron of the gene. Skipping of exon 16 in the encoded mRNA results in a frameshift in the coding sequence and the introduction of a premature stop codon. The encoded protein was not detectable in mutant fully grown oocytes, and the mutant mRNA was detectable only in trace amounts. (J:181834)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 7 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Marf1 Mutation:  79 strains or lines available
References
Original:  J:92463 JAX Reproductive Mutagenesis Program, Heritable mouse mutants from The Jackson Laboratory Reproductive Genomics Mutagenesis Program. MGI Direct Data Submission. 2004-7;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory