Marf1^m1Rpg
Chemically induced Allele Detail

Summary

• Symbol: Marf1^m1Rpg
• Name: meiosis regulator and mRNA stability 1; mutation 1, The Jackson Laboratory Reproductive Genomics Program
• MGI ID: MGI:3512917
• Synonyms: G1-375-18, marf1, Marf1^ENU, Marf1^ENU375-18
• Gene: Marf1 Location: Chr16:13927030-13977157 bp, - strand Genetic Position: Chr16, 9.69 cM
• Alliance: Marf1^m1Rpg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen. The molecular lesion is a G-to-T transversion mutation at the 5' splice donor site of the 16th intron of the gene. Skipping of exon 16 in the encoded mRNA results in a frameshift in the coding sequence and the introduction of a premature stop codon. The encoded protein was not detectable in mutant fully grown oocytes, and the mutant mRNA was detectable only in trace amounts. (J:181834)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	7 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Marf1 Mutation: 79 strains or lines available

References

• Original: J:92463 JAX Reproductive Mutagenesis Program, Heritable mouse mutants from The Jackson Laboratory Reproductive Genomics Mutagenesis Program. MGI Direct Data Submission. 2004-7
• All: 3 reference(s)