Prl8a2^tm1Soar
Targeted Allele Detail

Summary

• Symbol: Prl8a2^tm1Soar
• Name: prolactin family 8, subfamily a, member 2; targeted mutation 1, Michael J Soares
• MGI ID: MGI:3513194
• Gene: Prl8a2 Location: Chr13:27529656-27538199 bp, + strand Genetic Position: Chr13, 12.41 cM
• Alliance: Prl8a2^tm1Soar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117034
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2-6 of dPRP were replaced with a GFP and a neo gene. Absence of transcription was confirmed by Northern blot analysis, in situ hybridization, and RT-PCR. Absence of protein product was demonstrated by immunohistochemistry. (J:117034)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prl8a2 Mutation: 20 strains or lines available

References

• Original: J:117034 Alam SM, et al., A uterine decidual cell cytokine ensures pregnancy-dependent adaptations to a physiological stressor. Development. 2007 Jan;134(2):407-15
• All: 2 reference(s)