Tg(HBV-HCV)49Kko
Transgene Detail

Summary

• Symbol: Tg(HBV-HCV)49Kko
• Name: transgene insertion 49, Kazuhiko Koike
• MGI ID: MGI:3513426
• Synonyms: C49
• Transgene: Tg(HBV-HCV)49Kko Location: unknown
• Alliance: Tg(HBV-HCV)49Kko page

Transgene origin

• Strain of Origin: C57BL/6NJcl

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A 0.6 kb fragment containing the core protein from HCV was cloned downstream of HBV regulatory elements. this allele was associated with founder C49. 3-4 copies of the transgene were said to be incorporated into the genome, and expression was detected in the liver. (J:94426)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(HBV-HCV)49Kko

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:94426 Moriya K, et al., Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol. 1997 Jul;78(Pt 7):1527-31
• All: 5 reference(s)