Tg(rtetR-tetO-cre)40Mhz
Transgene Detail

Summary

• Symbol: Tg(rtetR-tetO-cre)40Mhz
• Name: transgene insertion 40, Martin Holzenberger
• MGI ID: MGI:3513452
• Synonyms: Meu40-Cre, MeuCre40, MeuCre40MH, meu-cre line 40
• Transgene: Tg(rtetR-tetO-cre)40Mhz Location: unknown
• Alliance: Tg(rtetR-tetO-cre)40Mhz page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(rtetR-tetO-cre)40Mhz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  bacteria	tetO

• Mutation details: This transgene uses the same construct as in Tg(rtetR-TetO-cre)1Mhz, however, it displayed a mosaic pattern early embryonic, ubiquitous (Meu) Cre expression that was not dependent on nor affected by doxycycline treatment. This line displayed a high level of partial Cre-lox recombination in all tissues examined. (J:94551)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	tetO (bacteria) Summary of all recombinase alleles driven by tetO.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

MeuCre44, MeuCre17, MeuCre48 are the lines represented by this transgene. See also J:69328.

References

• Original: J:94551 Leneuve P, et al., Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles. Nucleic Acids Res. 2003 Mar 1;31(5):e21
• All: 34 reference(s)