Ap3b2^tm1Bur
Targeted Allele Detail

Summary

• Symbol: Ap3b2^tm1Bur
• Name: adaptor-related protein complex 3, beta 2 subunit; targeted mutation 1, Margit Burmeister
• MGI ID: MGI:3513518
• Synonyms: Ap3b2^-
• Gene: Ap3b2 Location: Chr7:81110147-81143673 bp, - strand Genetic Position: Chr7, 45.71 cM
• Alliance: Ap3b2^tm1Bur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94942
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 5 through 12 were targeted and one-third of the coding region near the N terminus was removed. (J:94942)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ap3b2 Mutation: 66 strains or lines available

References

• Original: J:94942 Seong E, et al., Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain. Mol Biol Cell. 2005 Jan;16(1):128-40
• All: 5 reference(s)