Tg(Pcp2-cre)756Mro
Transgene Detail

Summary

• Symbol: Tg(Pcp2-cre)756Mro
• Name: transgene insertion 756, Silvia Marino
• MGI ID: MGI:3513599
• Synonyms: L7cre, L7cre756
• Transgene: Tg(Pcp2-cre)756Mro Location: unknown
• Alliance: Tg(Pcp2-cre)756Mro page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pcp2-cre)756Mro expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pcp2

• Mutation details: The transgene carried a cre cDNA fragment cloned into exon 4 of the Pcp2 gene and promoter. Transgenic mice show restricted expression of Cre recombinase in Purkinje cells. (J:77123)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pcp2 (species not specified) Summary of all recombinase alleles driven by Pcp2. Comparative matrix view of recombinase activities

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pcp2-cre)756Mro

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:77123 Marino S, et al., PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum. Development. 2002 Jul;129(14):3513-22
• All: 6 reference(s)