Sypl2^tm1Hta
Targeted Allele Detail

Summary

• Symbol: Sypl2^tm1Hta
• Name: synaptophysin like 2; targeted mutation 1, Hiroshi Takeshima
• MGI ID: MGI:3513758
• Synonyms: MG29^m1
• Gene: Sypl2 Location: Chr3:108119582-108133915 bp, - strand Genetic Position: Chr3, 46.87 cM, cytoband F3-H2
• Alliance: Sypl2^tm1Hta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:59188
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The promoter and the first exon were replaced by a neomycin selection cassette. Northern and western blot analysis were used to demonstrate an absence of transcript and protein encoded by this gene. (J:59188)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sypl2 Mutation: 21 strains or lines available

References

• Original: J:59188 Nishi M, et al., Abnormal features in skeletal muscle from mice lacking mitsugumin29. J Cell Biol. 1999 Dec 27;147(7):1473-80
• All: 5 reference(s)