Rtn4r^tm1Stmr
Targeted Allele Detail

Summary

• Symbol: Rtn4r^tm1Stmr
• Name: reticulon 4 receptor; targeted mutation 1, Stephen M Strittmatter
• MGI ID: MGI:3514018
• Synonyms: NGR^-
• Gene: Rtn4r Location: Chr16:17945506-17970272 bp, + strand Genetic Position: Chr16, 11.23 cM, cytoband B1
• Alliance: Rtn4r^tm1Stmr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94754
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neomycin resistance cassette. Northern and Western blot analysis confirmed the absence of both transcription and translation products. (J:94754)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn4r Mutation: 24 strains or lines available

References

• Original: J:94754 Kim JE, et al., Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury. Neuron. 2004 Oct 28;44(3):439-51
• All: 30 reference(s)