Fosl2^tm2Wag
Targeted Allele Detail

Summary

• Symbol: Fosl2^tm2Wag
• Name: fos-like antigen 2; targeted mutation 2, Erwin F Wagner
• MGI ID: MGI:3521818
• Synonyms: Fosl2^f, Fra-2^f
• Gene: Fosl2 Location: Chr5:32293145-32315186 bp, + strand Genetic Position: Chr5, 17.33 cM
• Alliance: Fosl2^tm2Wag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94393
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 and 4 were floxed. (J:125028)

Expression

In Mice Carrying this Mutation:	41 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fosl2 Mutation: 13 strains or lines available

References

• Original: J:94393 Karreth F, et al., The AP1 transcription factor Fra2 is required for efficient cartilage development. Development. 2004 Nov;131(22):5717-25
• All: 16 reference(s)