Adcyap1^tm1Clw
Targeted Allele Detail

Summary

• Symbol: Adcyap1^tm1Clw
• Name: adenylate cyclase activating polypeptide 1; targeted mutation 1, Christopher S Colwell
• MGI ID: MGI:3521845
• Synonyms: PACAP^-
• Gene: Adcyap1 Location: Chr17:93506448-93513967 bp, + strand Genetic Position: Chr17, 60.67 cM
• Alliance: Adcyap1^tm1Clw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94880
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3, 4 and part of 5 were replaced with a neomycin resistance cassette. RIA analysis confirmed the absence of protein product. (J:94880)

Tumor Data

List all tumor models in MMHCdb carrying Adcyap1^tm1Clw

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adcyap1 Mutation: 22 strains or lines available

References

• Original: J:94880 Colwell CS, et al., Selective deficits in the circadian light response in mice lacking PACAP. Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1194-201
• All: 16 reference(s)