Zbtb32^tm1Iho
Targeted Allele Detail

Summary

• Symbol: Zbtb32^tm1Iho
• Name: zinc finger and BTB domain containing 32; targeted mutation 1, I-Cheng Ho
• MGI ID: MGI:3522354
• Synonyms: ROGKO
• Gene: Zbtb32 Location: Chr7:30289106-30298334 bp, - strand Genetic Position: Chr7, 18.72 cM, cytoband B2-B3
• Alliance: Zbtb32^tm1Iho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94944
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2-5 and part of exon 6 were replaced with a neomycin resistance gene. Absence of protein product was confirmed via immunohistochemistry studies. (J:94944)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb32 Mutation: 27 strains or lines available

References

• Original: J:94944 Kang BY, et al., ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation. Mol Cell Biol. 2005 Jan;25(2):554-62
• All: 5 reference(s)