Myh9^tm1Maco
Targeted Allele Detail

Summary

• Symbol: Myh9^tm1Maco
• Name: myosin, heavy polypeptide 9, non-muscle; targeted mutation 1, Mary Anne Conti
• MGI ID: MGI:3522434
• Synonyms: A^-
• Gene: Myh9 Location: Chr15:77644788-77726315 bp, - strand Genetic Position: Chr15, 36.81 cM
• Alliance: Myh9^tm1Maco page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94940
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A PGK-neomycin cassette was inserted in exon 3. Absence of gene products was confirmed by Northern and Western blot analysis and by immunohistochemistry. (J:94940)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Myh9 Mutation: 219 strains or lines available

References

• Original: J:94940 Conti MA, et al., Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice. J Biol Chem. 2004 Oct 1;279(40):41263-6
• All: 4 reference(s)