Il27ra^tm1Fjs
Targeted Allele Detail

Summary

• Symbol: Il27ra^tm1Fjs
• Name: interleukin 27 receptor, alpha; targeted mutation 1, Frederic J de Sauvage
• MGI ID: MGI:3525439
• Synonyms: IL27-R^-, Il27ra-, TCCR^-
• Gene: Il27ra Location: Chr8:84756923-84769218 bp, - strand Genetic Position: Chr8, 40.26 cM, cytoband C3
• Alliance: Il27ra^tm1Fjs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:65439
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exons 2-8. Splenic RNA analyzed by Northern blot and RT-PCR showed no transcript was expressed from this allele. (J:65439)

Tumor Data

List all tumor models in MMHCdb carrying Il27ra^tm1Fjs

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il27ra Mutation: 29 strains or lines available

References

• Original: J:65439 Chen Q, et al., Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature. 2000 Oct 19;407(6806):916-20
• All: 23 reference(s)