Tg(MMTV-cre)7Mul
Transgene Detail

Summary

• Symbol: Tg(MMTV-cre)7Mul
• Name: transgene insertion 7, William J Muller
• MGI ID: MGI:3525443
• Synonyms: MMTV-Cre, MMTV-Cre7
• Transgene: Tg(MMTV-cre)7Mul Location: unknown
• Alliance: Tg(MMTV-cre)7Mul page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(MMTV-cre)7Mul expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  virus	MMTV

• Mutation details: This transgene contains the Cre cDNA fused to the MMTV-LTR promoter containing sequence, and an HSV derived polyA tail. Transgene expression was detected primarily in the mammary gland and accessory male sex organs. Some Cre mediated recombination was also observed in the spleen and salivary glands of mice carrying this allele. (J:61202)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	MMTV (virus) Summary of all recombinase alleles driven by MMTV.

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-cre)7Mul

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:61202 Andrechek ER, et al., Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3444-9
• All: 57 reference(s)