Rb1cc1^tm1.1Guan
Targeted Allele Detail

Summary

• Symbol: Rb1cc1^tm1.1Guan
• Name: RB1-inducible coiled-coil 1; targeted mutation 1.1, Jun-Lin Guan
• MGI ID: MGI:3526069
• Synonyms: Fip200^flox
• Gene: Rb1cc1 Location: Chr1:6284858-6346599 bp, + strand Genetic Position: Chr1, 1.89 cM, cytoband A2
• Alliance: Rb1cc1^tm1.1Guan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:114498
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 4 and 5 were flanked by loxP sites. (J:114498)

Expression

In Mice Carrying this Mutation:	31 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rb1cc1 Mutation: 84 strains or lines available

References

• Original: J:114498 Gan B, et al., Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. J Cell Biol. 2006 Oct 9;175(1):121-33
• All: 44 reference(s)