Depp1^{tm1(EGFP/cre)Shin}
Targeted Allele Detail

Summary

• Symbol: Depp1^{tm1(EGFP/cre)Shin}
• Name: DEPP1 autophagy regulator; targeted mutation 1, Donghun Shin
• MGI ID: MGI:3526084
• Synonyms: Depp^EGFP-Cre
• Gene: Depp1 Location: Chr6:116627645-116629808 bp, + strand Genetic Position: Chr6, 53.83 cM
• Alliance: Depp1^{tm1(EGFP/cre)Shin} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144155
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Depp1^{tm1(EGFP/cre)Shin} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Depp1 (MGI:1918730)

• Mutation details: The whole coding region was replaced with EGFP-Cre and an FRT flanked PGK-neo. Absence of transcription was confirmed by QPCR. (J:144155)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Depp1 (mouse) Summary of all recombinase alleles driven by Depp1. Alliance mouse Depp1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Depp1 Mutation: 20 strains or lines available

References

• Original: J:144155 Shin D, et al., Isolation of arterial-specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells. Dev Dyn. 2005 Aug;233(4):1589-604
• All: 1 reference(s)