Gsdma3^Rco2
Chemically induced Allele Detail

Summary

• Symbol: Gsdma3^Rco2
• Name: gasdermin A3; Reduced coat 2
• MGI ID: MGI:3526126
• Synonyms: Rco2
• Gene: Gsdma3 Location: Chr11:98517186-98529052 bp, + strand Genetic Position: Chr11, 62.21 cM
• Alliance: Gsdma3^Rco2 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Sequence analysis revealed a T to C transition in nucleotide position 1110, changing the transcript from CTC to CCC in exon 10, and changing leucine 343 to proline. (J:93938)
• Inheritance: Dominant

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsdma3 Mutation: 26 strains or lines available

References

• Original: J:93938 Runkel F, et al., The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3. Genomics. 2004 Nov;84(5):824-35
• All: 1 reference(s)