Hoxd1^tm1Mrc
Targeted Allele Detail

Summary

• Symbol: Hoxd1^tm1Mrc
• Name: homeobox D1; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:3526155
• Gene: Hoxd1 Location: Chr2:74593324-74595486 bp, + strand Genetic Position: Chr2, 44.13 cM
• Alliance: Hoxd1^tm1Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170402
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neo cassette was inserted into exon 2. The absence of transcript expression was confirmed by in situ hybridization on dorsal root ganglia samples. (J:170402)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd1 Mutation: 16 strains or lines available

References

• Original: J:170402 Guo T, et al., An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. Nat Neurosci. 2011 Jan;14(1):31-6
• All: 1 reference(s)