Rnf17^tm1Jw
Targeted Allele Detail

Summary

• Symbol: Rnf17^tm1Jw
• Name: ring finger protein 17; targeted mutation 1, Jeremy Wang
• MGI ID: MGI:3526166
• Synonyms: Rnf17^-
• Gene: Rnf17 Location: Chr14:56640107-56762489 bp, + strand Genetic Position: Chr14, 28.21 cM
• Alliance: Rnf17^tm1Jw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101737
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first two exons were replaced by PGK1-Neo, removing the ATG, sequence encoding the RING finger and part of its Mad-binding domain. Absence of protein was confirmed in mutant testis. (J:101737)

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf17 Mutation: 78 strains or lines available

References

• Original: J:101737 Pan J, et al., RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis. Development. 2005 Sep;132(18):4029-39
• All: 2 reference(s)