Fgf10^tm1.1Sms
Targeted Allele Detail

Summary

• Symbol: Fgf10^tm1.1Sms
• Name: fibroblast growth factor 10; targeted mutation 1.1, Suzanne L Mansour
• MGI ID: MGI:3526181
• Gene: Fgf10 Location: Chr13:118851199-118928651 bp, + strand Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
• Alliance: Fgf10^tm1.1Sms page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150706
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A Neo+KanR cassette was placed in intron 1 and exon 2 was flanked by loxP sites. Exon 2 was subsequently removed by cre-mediated recombination. (J:150706)

Expression

In Mice Carrying this Mutation:	85 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf10 Mutation: 33 strains or lines available

References

• Original: J:150706 Abler LL, et al., Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung. Dev Dyn. 2009 Jul 17;238(8):1999-2013
• All: 9 reference(s)