Zpr1^tm1Rjd
Targeted Allele Detail

Summary

• Symbol: Zpr1^tm1Rjd
• Name: ZPR1 zinc finger; targeted mutation 1, Roger J Davis
• MGI ID: MGI:3526216
• Synonyms: Zpr1^-
• Gene: Zpr1 Location: Chr9:46184362-46193941 bp, + strand Genetic Position: Chr9, 25.38 cM
• Alliance: Zpr1^tm1Rjd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97582
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo replaced exon 1. (J:97582)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zpr1 Mutation: 20 strains or lines available

References

• Original: J:97582 Gangwani L, et al., ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies. Mol Cell Biol. 2005 Apr;25(7):2744-56
• All: 3 reference(s)