Etnk2^tm1Mkar
Targeted Allele Detail

Summary

• Symbol: Etnk2^tm1Mkar
• Name: ethanolamine kinase 2; targeted mutation 1, Suzanne Jackowski
• MGI ID: MGI:3526407
• Synonyms: Etnk2^-
• Gene: Etnk2 Location: Chr1:133291308-133308056 bp, + strand Genetic Position: Chr1, 57.91 cM
• Alliance: Etnk2^tm1Mkar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117170
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The Neo resistance gene (NEO) cassette was inserted into exon-3 of the gene to replace 66 bp. (J:117170)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etnk2 Mutation: 23 strains or lines available

References

• Original: J:117170 Tian Y, et al., Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2. J Biol Chem. 2006 Sep 22;281(38):28438-49
• All: 1 reference(s)