Fzd9^tm1Uta
Targeted Allele Detail

Summary

• Symbol: Fzd9^tm1Uta
• Name: frizzled class receptor 9; targeted mutation 1, Uta Francke
• MGI ID: MGI:3526665
• Synonyms: Fzd9^-
• Gene: Fzd9 Location: Chr5:135277792-135279901 bp, - strand Genetic Position: Chr5, 75.08 cM
• Alliance: Fzd9^tm1Uta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98133
• Parent Cell Line: JM-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced the coding exon. Northern blot analysis confirmed the absence of transcription. (J:98133)

Disease models

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fzd9 Mutation: 37 strains or lines available

References

• Original: J:98133 Ranheim EA, et al., Frizzled 9 knock-out mice have abnormal B-cell development. Blood. 2005 Mar 15;105(6):2487-94
• All: 5 reference(s)