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Arr3tm1Chcr
Targeted Allele Detail
Summary
Symbol: Arr3tm1Chcr
Name: arrestin 3, retinal; targeted mutation 1, Cheryl M Craft
MGI ID: MGI:3527130
Synonyms: Arr4-
Gene: Arr3  Location: ChrX:99649103-99662099 bp, + strand  Genetic Position: ChrX, 43.72 cM, cytoband C2
Alliance: Arr3tm1Chcr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139694
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe lacZ/neo cassette was inserted at the 5'end of exon 1 and replaces about 2 kb of the gene sequence including exons 1-5. The absence of protein expression was confirmed by immunohistochemistry on eye sections. (J:139694)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arr3 Mutation:  11 strains or lines available
References
Original:  J:139694 Nikonov SS, et al., Mouse cones require an arrestin for normal inactivation of phototransduction. Neuron. 2008 Aug 14;59(3):462-74
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory