Grin1^tm1Rpa
Targeted Allele Detail

Summary

• Symbol: Grin1^tm1Rpa
• Name: glutamate receptor, ionotropic, NMDA1 (zeta 1); targeted mutation 1, Richard D Palmiter
• MGI ID: MGI:3527183
• Synonyms: Grin1^lox
• Gene: Grin1 Location: Chr2:25181193-25209199 bp, - strand Genetic Position: Chr2, 17.14 cM
• Alliance: Grin1^tm1Rpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:145468
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 11 through 23 were floxed and followed by a neo cassette. (J:145468)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grin1 Mutation: 66 strains or lines available

References

• Original: J:145468 Zweifel LS, et al., Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron. 2008 Aug 14;59(3):486-96
• All: 4 reference(s)